By Marlene L. Rose

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If one examines the blood of patients during myocardial ischemia,44 the levels of soluble ICAM-1 are increased, suggesting that it may also play a role in acute events, as well as in long-term pathogenesis. 45 VCAM-146 This molecule, Vascular Cell Adhesion Molecule-1, 110 kD in size is, like ICAM-1, a member of the immunoglobulin supergene family. Its expression is stimulated by IL1, TNFα,47 LPS, IL4, IFNγ and lysophosphatidylcholine. Low shear stress48 has also been shown to induce its expression.

Angina and threatened acute myocardial infarction after cardiac transplantation. Am Heart J 1990; 119:1195-7. 27. Schroeder JS, Hunt SA. Chest pain in hearttransplant recipients. N Engl J Med 1991; 324:1805-7. 28. Grinstead WC, Smart FW, Pratt CM et al. Detection of asymptomatic myocardial ischemia in a heart transplant patient before sudden death. J Heart Lung Transplant 1991; 10:1026-8. 29. Gao SZ, Schroeder JS, Hunt SA et al. Acute myocardial infarction in cardiac transplant recipients. Am J Cardiol 1989; 64:1093-7.

Coronary angioplasty in cardiac transplant patients. Results of a multicenter study. Circulation 1992; 86:458-62. 162. Swan JW, Norell M, Yacoub M et al. Coronary angioplasty in cardiac transplant recipients. Eur Heart J 1993; 14:65-70. 163. Cusick D, Davidson C, Frohlich T et al. Coronary artery stenting postcardiac transplant: A report of two cases. Cathet Cardiovasc Diagn 1997; 40:92-6. 164. Jain SP, Ramee SR, White CJ et al. Coronary stenting in cardiac allograft vasculopathy. J Am Coll Cardiol 1998; 32: 1636-40.

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