By L. Morgenstern (auth.), Jonathan R. Hiatt M.D., Edward H. Phillips M.D., Leon Morgenstern M.D. (eds.)
Surgical ailments of the Spleen written and edited through across the world popular scientists could be a masterpiece for any establishment. It offers an up-to-date multidisciplinary overview of ailments of the spleen. specialists within the box have customed their chapters to extra ease the readers figuring out delivering the entire details had to growth during this quarter. assorted sections on uncomplicated innovations, particular splenic ailments and operative innovations conceal new points in immunology, infectious, demanding and neoplastic conditions.
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Sample text
Myeloproliferative Disorders The myeloproliferative disorders include polycythemia vera (PV), agnogenic myeloid metaplasia (or myelofibrosis with myeloid metaplasia) (AMM), essential thrombocythemia (ET), and chronic myelogenous leukemia (CML). The reasons for splenomegaly differ in each of these disorders. In the uncomplicated erythrocytotic phase of PV, the spleen is enlarged because of engorgement of the organ as part of the increased blood volume that occurs in this disorder [35]. S. Neiman 3386 mmrlllllllllllllllllil ', Fig.
Systemic lupus erythematosis F. Chronic uremia with hypersplenism (hemodialyzed) G. Viral hepatitis H. Many systemic infections and chronic inflammatory states ITP, immune thrombocytopenic purpura; AIHA, antibody-induced hemolytic anemia. Fig. 6. Photomicrograph of a trabecular artery and vein adjacent to white pulp in a patient with infectious mononucleosis. There is a pleomorphic infiltrate of small lymphoid cells, plasma cells, and large transformed lymphocytes. Note that the lymphoid cells infIltrate the wall of the blood vessel.
The role of frozen sections in splenic diagnosis is somewhat controversial. Touch imprints are frequently more reliable than an extremely difficult technical process of obtaining a frozen section in an enlarged bloody organ. Therefore, frozen sections of spleens should be discouraged where possible. However, if diagnostic splenectomy reveals the presence of tumor masses or focal lesions in the spleen, frozen section may be a valuable procedure. The type of fixative used in processing sections of spleen is of less importance than the care taken in fixation.