By Lisette Leyton Ph.D., James S. Hagood M.D. (auth.), Vladimir Berezin, Peter S. Walmod (eds.)

Cell Adhesion Molecules: Implications in Neurological illnesses includes evaluation articles on fresh advancements within the box of neural mobilephone adhesion molecules (CAMs). the focus is at the position of mobile adhesion molecules in numerous neurological and neurodegenerative ailments. this attitude has been basically missed in lately released books on neural CAMs. moreover, the members disguise many newly pointed out mobilephone adhesion molecules and a few that experience now not got a lot realization lately. This books fills an immense hole within the at the moment to be had literature. ​

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Cell Adhesion Molecules: Implications in Neurological Diseases

Cellphone Adhesion Molecules: Implications in Neurological ailments comprises evaluate articles on contemporary advancements within the box of neural mobile adhesion molecules (CAMs). the main target is at the position of mobile adhesion molecules in numerous neurological and neurodegenerative illnesses. this angle has been primarily ignored in lately released books on neural CAMs.

Additional resources for Cell Adhesion Molecules: Implications in Neurological Diseases

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Thy-1 thus appears to regulate the trafficking and partitioning of signaling molecules into and out of lipid raft domains, thereby modulating signaling networks associated with the cytoskeleton. In this way Thy-1 may act alternately as an inhibitor of signaling molecules such as SFKs, by sequestering them, or as a facilitator of signaling, by regulating their trafficking. Thy-1 also associates with proteins in the inner leaflet of the plasma membrane via myristoylated and palmitoylated posttranslational modifications, such as the 14 L.

Biochem Biophys Res Commun 331(2):557–561 Couchman JR, Woods A (1999) Syndecan-4 and integrins: combinatorial signaling in cell adhesion. J Cell Sci 112(Pt 20):3415–3420 Deininger SO, Rajendran L, Lottspeich F, Przybylski M, Illges H, Stuermer CA, Reuter A (2003) Identification of teleost Thy-1 and association with the microdomain/lipid raft reggie proteins in regenerating CNS axons. Mol Cell Neurosci 22(4):544–554 Doherty P, Singh A, Rimon G, Bolsover SR, Walsh FS (1993) Thy-1 antibody-triggered neurite outgrowth requires an influx of calcium into neurons via N- and L-type calcium channels.

BMC Dev Biol 1:11 16 L. S. Hagood Burridge K, Chrzanowska-Wodnicka M (1996) Focal adhesions, contractility, and signaling. Annu Rev Cell Dev Biol 12:463–518. 463 Campsall KD, Mazerolle CJ, De Repentingy Y, Kothary R, Wallace VA (2002) Characterization of transgene expression and Cre recombinase activity in a panel of Thy-1 promoter-Cre transgenic mice. Dev Dyn 224(2):135–143 Cao Q, Abeysinghe H, Chow O, Xu J, Kaung H, Fong C, Keng P, Insel RA, Lee WM, Barrett JC, Wang N (2001) Suppression of tumorigenicity in human ovarian carcinoma cell line SKOV-3 by microcell-mediated transfer of chromosome 11.

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