By Stefan Mircea Iencean
Intracranial high blood pressure (ICH) is the commonest reason for scientific deterioration and demise for neurological and neurosurgical sufferers. there are numerous factors of raised intracranial strain (ICP) and elevated ICP can produce intracranial high blood pressure syndromes. tracking of intracranial strain and advances in investigations of the principal frightened method have resulted in new suggestions and systemisations in intracranial high blood pressure. The descriptive category of the intracranial high blood pressure has been changed by means of an etio-pathogenic type with 4 major teams. Parenchymatous Intracranial high blood pressure, within the extending intracranial methods (cerebral tumours, intracranial haematoma, cerebral abscesses, etc.), in nerve-racking mind edema, in hypotoxic mind edema, as a rule intoxications with neurotoxins (endogenous or exogenous), and so forth. Vascular Intracranial high blood pressure is brought on by the problems of cerebral blood movement after which the mind edema or / and mind swelling appears to be like. The vascular intracranial high blood pressure happens in: vascular cerebral ailments - cerebral venous thrombosis or in cerebral ischaemic stroke and in - extracerebral vascular ailments as hypertensive encephalopathies. Intracranial high blood pressure is brought on by the problems of the CSF dynamics ( hydrocephalus etc). Idiopathic Intracranial high blood pressure. The remedy of intracranial high blood pressure relies on the kind of intracranial high blood pressure and at the degree of the ailment.
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Sample text
The capillaries of the choroid plexuses are different from the rest of the cerebral capillaries because they have fenestrations by which the substances pass from the capillary lumen towards the ependymal epithelium. The ependymal cells that cover the choroid capillaries present circumferential occlusion junctions that join them together and allow a selective permeability. The ependymal cells of the choroid plexuses have a voluminous nucleus, they have numerous cellular organelles (mitochondrias, lyso-somes, pinocytary vesicles) and an abundant cytoplasm with a rich enzymatic content, which underlines an intense metabolic activity for the elaboration of the cerebrospinal fluid.
The intracranial pressure is rapidly influenced by the variations of the cerebral blood volume, which occurs as a factor of instability for ICP. The connection between the cerebral vessels, the dural sinuses and the great vessels of the throat makes it possible for the venous pressure increases, which are induced by the modifications from the level of the thorax or of the throat, to be sent intracranially, being able to influence the intracranial pressure. 5. Brain Blood Barrier The brain blood barrier (BBB) represents the morpho-functional system with a protecting role, which separates the nervous parenchyma from the blood circulation, in order to secure and control the cerebral homeostasis.
The blood-cerebrospinal fluid barrier. CRC Press, 2005 Chapter III Intracranial Pressure 1. General Considerations The intracranial pressure is the intrinsic pressure developed by the endocranial-spinal structures (nervous parenchyma, blood and cerebrospinal fluid), as a result of the tensional (expanding) forces that the intradural content exercises on the limiting dural cover; its variations reflect the relationship between the cranio-spinal content changes and the capacity of accommodation to a supplementary volume.