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Additional resources for Congenital Heart Disease - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References
Example text
Because of tinman's principal role in heart development, we plan to further elucidate its function and regulation (Aim 1). In a molecular screen, we further propose to identify transacting factors that are necessary for cardiac tinman expression, which is likely to yield new players in heart development (Aim 2), and in addition, may lead to new parallel mechanisms in vertebrate cardiogenesis. In a genetic screen, we further plan to identify new gene functions that are in control of and participate during cardiac differentiation and physiological function (Aim 3).
Further, an imbalance between pulmonary and systemic blood flow in these patients due to stenosis of the shunt, growth of the patient, or inappropriate systemic or pulmonary vascular resistance can be life-threatening. We believe that serial quantitative measurements of volume shunt flow will lead to improved management of these patients and will result in reduced mortality, morbidity, and cost of care. Currently, the only method available to measure quantitative flow in these shunts is angiography, an invasive procedure that is suitable only in limited circumstances.
Thus, this Institutional Training Grant is crucial to ongoing efforts to bring the considerable scientific resources of our institution to bear on problems of cardiovascular relevance. Generate_Screen • Project Title: MINORITY PREDOCTORAL FELLOWSHIP PROGRAM Principal Investigator & Institution: Rivera-Feliciano, Jose; Cell Biology; Harvard University (Medical School) Medical School Campus Boston, Ma 02115 Timing: Fiscal Year 2002; Project Start 30-SEP-2002 36 Congenital Heart Disease Summary: The morphology and physiology of the heart have fascinated scientists for decades.