By Jaime M. Monti, S. R. Pandi-Perumal, S. Chokroverty
This publication deals a finished yet hugely readable compilation of papers at the function of dopamine in sleep and sleep issues. prime specialists in sleep drugs, psychiatry and neuroendocrinology supply a wide point of view at the box, from demonstrated theories to the newest study advances. as a result, it represents an interdisciplinary, state of the art consultant for sleep problem experts, sleep researchers, psychiatrists, neurologists, pulmonologists, psychologists, and behavioral sleep medication specialists.
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Extra info for Dopamine and Sleep: Molecular, Functional, and Clinical Aspects
Example text
In Drosophila, mutations in DAT, resulting in reduced dopamine clearance, showed a greater sleep rebound following sleep deprivation (Greenspan et al. 2001). Effects of dopamine on sleep homoestasis in this species appear to require downregulation of A-type potassium channels of the Shaker family and upregulation of two-pore leak potassium channels (Pimentel et al. 2016). In the basal forebrain of rats, levels of dopamine metabolites are increased during SD (Zant et al. 2011). Sleep deprivation in humans was associated with a decrease in dopamine D2/D3 receptors in the nucleus accumbens, which would be consistent with an increase in sleepiness, if dopamine inhibits this sleep-promoting area via these receptors.
J Neurosci 17:2519–2530 Theohar C, Fischer-Cornelssen K, Brosch H, Fischer E, Petrovic D (1981) A comparative, multicenter trial between bromocriptine and amitriptyline in the treatment of endogenous depression. Arzneimittel-Forschung 32:783–787 Trampus M, Ongini E (1990) The D1 dopamine receptor antagonist SCH 23390 enhances REM sleep in the rat. Neuropharmacology 29:889–893 Trampus M, Ferri N, Monopoli A, Ongini E (1991) The dopamine D 1 receptor is involved in the regulation of REM sleep in the rat.
J Clin Psychiatr 66:1254–1269 Ungerstedt U (1971) Stereotaxic mapping of the monoamine pathways in the rat brain. Acta Physiol Scand Suppl 367:1–48 Usiello A, Baik J-H, Rougé-Pont F, Picetti R, Dierich A, LeMeur M, Piazza PV, Borrelli E (2000) Distinct functions of the two isoforms of dopamine D2 receptors. Nature 408:199–203 Wang S, Liao C, Meng W, Huang Q, Li D (2015) Activation of D1-like dopamine receptors increases the NMDA-induced gain modulation through a PKA-dependent pathway in the premotor nucleus of adult zebra finches.