By Andrew M. Freeman, Howard D. Weinberger

This publication will offer, for the 1st time on hand, a concise yet excessive yield subject assessment of cardiac sarcoidosis from hazard elements to the advance of the disorder via remedies. The booklet will comprise recommendations which are rising and people who are actually identified at the subject, and may use actual international examples to assist illustrate most sensible practices within the administration of this disorder entity.

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Additional resources for Cardiac Sarcoidosis: Key Concepts in Pathogenesis, Disease Management, and Interesting Cases

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323. 5. Chapelon-Abric C, de Zuttere D, Duhaut P, et al. Cardiac sarcoidosis: a retrospective study of 41 cases. Medicine (Baltimore). 2004;83:315. 6. Yoshida Y, Morimoto S, Hiramitsu S, et al. Incidence of cardiac sarcoidosis in Japanese patients with high-degree atrioventricular block. Am Heart J. 1997;134:382. 7. Kunavarapu C, Bloomfield DM. Role of noninvasive studies in risk stratification for sudden cardiac death. Clin Cardiol. 2004;27(4):192–7. 8. Iravanian S, Arshad A, Steinberg JS. Role of electrophysiologic studies, signal-averaged electrocardiography, heart rate variability, T-wave alternans, and loop recorders for risk stratification of ventricular arrhythmias.

Patients with advanced cardiac sarcoidosis may have “burnt out” disease with no (or little) FDG uptake. Such patients are more likely to have left ventricular systolic dysfunction. Patients with large amount of scar and reduced ejection fraction are less likely to have an improvement in ejection fraction following immunosuppressive therapy. 7. When interpreting FDG PET studies, it is essential to also acquire and interpret whole body FDG data in order to identify if there is any active extra cardiac disease.

9] Supported by Demeure et al. [8] Supported by Cheng et al. [7] Suggest at least 18 h fast Supported by Morooka et al. [15] Inferior to HFLC diet or LC diet followed by fast [7, 8] Dose 50 IU/kg used in some studies, but lower doses may also be effective (avoid administering in dextrose); inferior to long term fasting [15] followed by a fast resulted in greater reduction in SUV (versus a controlled group of patients following an unrestricted diet) than a high fat low carbohydrate diet in which patients also drank a 250 cc beverage of mostly non-saturated fat 1 h prior to FDG injection [7].

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