By ML Kulkarni
This can be the first variation of the publication supplementations in well-being and ailment. supplementations are offered in a simplified approach with assistance from prime quality diagrams, pictures and tables. The textual content is entire, up-to-date and to the purpose. Biochemistry and metabolism, resources, requirement, capabilities, influence on immunity, interplay with different nutrition, epidemiology, deficiency, hypervitaminosis and teratogenicity of each Read more...
Prelims; Chapter-01; Chapter-02; Chapter-03; Chapter-04; Chapter-05; Chapter-06; Chapter-07; Appendix; Index
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Extra info for Vitamins in Health and Disease
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Bottle-fed children are at a greater disadvantage, particularly if they receive unfortified skimmed milk or whole milk, over diluted with water. After 4 to 6 months of age, the child requires supplementary feeds with foods rich in vitamin A. Due to reasons like ignorance and cost, these may not be consumed in adequate quantities. Further in children, deficiency may occur due to intestinal infestations and infections, respiratory infections, tuberculosis and measles. These increase metabolic demand, precipitate protein-energy malnutrition (PEM) and interfere with storage, transport and utilization of vitamins.
It can be used to screen and follow up patients on treatment. The standard indices of clinical status include serum-retinol levels, serum-retinol: RBP molar ratio, Darkfield adaptation testing, slit lamp 30 Vitamins in Health and Disease examination, liver levels of retinol and retinyl esters and relative dose response test (RDR). Finally, CIC has been used to assess deficiency. The earliest evidence of depletion is lowering of liver store (normally about 100 microgram/gm fresh liver). The retinol: RBP molar ratio is a tool to differentiate deficiency in cholestasis.
Cholecal- Vitamin D 43 ciferol is the naturally occurring (preformed) vitamin D in animal fats and fish liver oils. It is also derived from the exposure to UV rays of sunlight, which converts cholesterol in the skin to vitamin D. 1 mg of vitamin D3 = 40,000 IU. 5 × 10-5 mg Metabolism of Vitamin D The precursor of vitamin D3 is 7-dehydrocholesterol (7-DHC). Varying concentrations of this are stored in the layers of the epidermis mainly in stratum epinosum and stratum basale. On exposure to UV radiation of 270 to 300 nm, stored 7-DHC is converted to previtamin D3.