By Clemens Van Blitterswijk, Jan De Boer
Tissue Engineering isa entire creation to the engineering and organic facets of this severe topic. With contributions from the world over popular authors, it offers a wide standpoint on tissue engineering for college students coming to the topic for the 1st time. as well as the foremost subject matters lined within the past version, this replace additionally comprises new fabric at the regulatory professionals, advertisement issues in addition to new chapters on microfabrication, materiomics and cell/biomaterial interface.
- Effectively reports significant foundational subject matters in tissue engineering in a transparent and available fashion
- Includes cutting-edge experiments awarded in break-out bins, bankruptcy pursuits, bankruptcy summaries, and a number of selection inquiries to reduction learning
- New version comprises fabric on regulatory gurus and advertisement issues in tissue engineering
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Additional resources for Tissue Engineering, Second Edition
Sample text
In many published articles, the in vitro and in vivo differentiation of human pluripotent stem cells has been described. , 2006) have all been successfully derived in the laboratory. Levenberg et al. (2003) demonstrated the differentiation of human ES cells on polymeric scaffolds into three-dimensional structures with characteristics of developing neural tissues, cartilage, liver, or blood vessels. 1 Application of Mouse Pluripotent Stem Cells It is obvious that mouse pluripotent stem cells will never find clinical applications.
MSCs can differentiate into cells that form bone, cartilage, and fat. n Oligopotent stem cells can differentiate into two or more lineages, for example, neural stem cells that can form a subset of neurons in the brain. n Unipotency is the ability to form cells of a single lineage, for example, spermatogonial stem cells. n The term omnipotence is not used for stem cells, but is used in religions as one of the God’s characteristics. n Differentiation is the process whereby stem cells transform into more specialized cell types and can perform new functions through the expression of new genes, mRNA, and proteins.
A metastable state best describes the different states, position, or stages stem cells find themselves as they move into different environments for extended periods. 10. The developmental potential of a stem cell can be changed by the influence of local factors and time spent in a particular environment. If the cell moves to a new location, it may retain some influence of its previous environment for a period of time. 13). 6 PLURIPOTENT STEM CELLS Pluripotent stem cells can be isolated from embryos, germ cell progenitors of sperm, and fertilized egg or they can be derived from cells in culture through genetic engineering.