By Debra Niehoff

Cells talk—and scientists are listening. some of the most fascinating themes in molecular biology, biochemical communique is the cornerstone of contemporary drugs and the mainstay of state of the art pharmaceutical learn. for almost a century, researchers were straining to listen to the whispered conversations between cells, hoping to grasp the fundamentals in their language. They recognize that if we will decipher and translate this mobile chatter, we've got the possibility of sending indications of our personal that can fix wounds, decrease ldl cholesterol, keep watch over insulin degrees, or maybe block the copy of melanoma cells. the chances are remarkable.

The Language of existence unearths the non-public conversations of cells. in preference to phrases, even if, cells use chemical compounds, linking molecule to molecule to build sentences that obey formal principles of grammar and syntax as binding as those who govern our personal spoken and written language. in the course of the alternate and interpretation of chemical indications, they document each newsworthy occasion, list each reminiscence, reply to each physically harm.

If you have ever questioned how your physique copes with tension and alter, why you cannot shed some pounds, or shake unreasonable fears; if you may have reflected the origins of melanoma or the epidemic of diabetes; or if you've got wanted for a glimpse into the way forward for medication, this can be a ebook you need to learn. Debra Niehoff examines the conversation breakdowns that underlie a few of our commonest and intractable problems and exhibits how intervening in those crises through sending signs of our personal not just provides us the medicine to remedy what ails us, yet gives you more beneficial and higher detailed drugs sooner or later.

The Language of existence blends the imaginative and prescient of technological know-how with the poetry of lifestyles itself. it's a terrific tale of discovery that artfully conveys the epic of the constructing embryo, the miracle of the human mind, and the tales of battles waged via cells at the entrance traces of a endless struggle opposed to illness.

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Additional info for The Language Of Life. How Cells Communicate In Health & Disease

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Cells of the immune system improvised signals from the dismembered bodies of pathogens. Even death had its own dialect. To find these new signals, eukaryotic cells, like bacteria, didn’t have to look any farther than their own backyards. Built from chemicals, operated and maintained by chemicals, and fueled by chemical reactions, they lived in a dictionary. If a stray metabolite, a common nutrient, or a by-product already on hand wasn’t quite right, or if they were still at a loss for words, they could always turn to proteins for ideas.

A new social contract arrived along with the new furniture. Bacteria, eager to cohabitate, have never married—even those who settle in cities don’t hesitate to move on if times get tough. ” Their alliances were indissoluble, their commitment to their colleagues, unequivocal. Some—these would become plants—decided good fences make good neighbors after all and surrounded each of their cells with a cocoon of cellulose. Others—the clan that biologists call “metazoans” and we know as animals—forswore rigid walls that prevented real intimacy for good.

Elemental patterns and established rules of syntax, as familiar to E. coli as they are to human beings, constitute the universal grammar, part of the legacy of every cell. A SURFEIT OF SIGNALS Feeling under the weather? Tired, feverish, congested? Today, a doctor would probably attribute your symptoms to this season’s flu virus. If you were a patient in ancient Greece, however, your physician would have known nothing of viruses and infections. He would have blamed the problem on an imbalance in bodily secretions called humors, each representing one of the four elements thought to compose all matter: yellow bile, associated with fire; phlegm, cold and wet like water; blood, corresponding to air; and black bile, dark and inert as earth.

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