By edited by J. Paulo Davim.

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Xxxvii The design and manufacture of medical devices He is Editor of the subject area ‘Digital Instruments Standardization’ for the Elsevier Journal Computer Standards & Interfaces. He has published more than 160 scientific papers in journals and national and international conference proceedings. Pasquale Arpaia (Corresponding Author) Department. it Pasquale Cimmino Pasquale Cimmino gained an MD in Electrical Engineering at the University of Napoli Federico II. From 2000, he worked for Siemens and from 2003 at ST Micreolectronics.

Her research has focused on the application of thermoplastic polymers as encapsulation materials for active implantable medical devices and includes establishing the barrier performance and hermeticity of PEEK material to water vapour, and examining viable joining techniques for medical polymers. au xxxvi About the contributors Natalie L. James Natalie L. James has a BSc from the University of Sydney and MBiomedE and PhD awards from the University of New South Wales. She has extensive experience in the medical device industry, specifically cardiovascular and hearing devices, in the development and assessment of materials and biocompatibility.

Almost everyone has a simple biomaterial inserted into the body. For example, a dental filling, according to the definitions already given, is a biomaterial. However, as the human population is ageing, there is a greater requirement for more complex implants. Implantable devices are often employed in order to modify the shape, appearance or structure of the body (Williams, 2003). These include replacement of joints and, recently, cardiovascular implants such as stents and artificial heart valves.

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