By Joseph D. Bronzino

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Biomedical Engineering
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References Bhagavan NV. 1992. Medical Biochemistry. Boston, Jones and Bartlett. Beall HPT, Needham D, Hochmuth RM. 1993. Volume and osmotic properties of human neutrophils. Blood 81(10):2774–2780. Caro CG, Pedley TJ, Schroter RC, Seed WA. 1978. The Mechanics of the Circulation. New York, Oxford University Press. Chandran KB. 1992. Cardiovascular Biomechanics. New York, New York University Press. Frausto da Silva JJR, Williams RJP. 1993. The Biological Chemistry of the Elements. New York, Oxford University Press/Clarendon.

Principles of Anatomy and Physiology, 7th ed. New York, HarperCollins. © 2000 by CRC Press LLC Cramp, G. , Carson E. R . ” The Biomedical Engineering Handbook: Second Edition. Ed. Joseph D. 2 Hormones Acting at the Cell Surface • Hormones Acting Within the Cell Derek G. Cramp City University, London Ewart R. 3 Endocrine System: Some Other Aspects of Regulation and Control Negative Feedback • Positive Feedback • Rhythmic Endocrine Control The body, if it is to achieve optimal performance, must possess mechanisms for sensing and responding appropriately to numerous biologic cues and signals in order to control and maintain its internal environment.

1), each being one self-contained pumping station, but the two being connected in series. The left side of the heart drives oxygen-rich blood through the aortic semilunar outlet valve into the systemic circulation, which carries the fluid to within a differential neighborhood of each cell in the body—from which it returns to the right side of the heart low in oxygen and rich in carbon dioxide. The right side of the heart then drives this oxygen-poor blood through the pulmonary semilunar (pulmonic) outlet valve into the pulmonary circulation, which carries the fluid to the lungs—where its oxygen supply is replenished and its carbon dioxide content is purged before it returns to the left side of the heart to begin the cycle all over again.

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