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Phase III trials for any drug tend to be costly and difficult to administer. And the AIDS trials are especially challenging because of an ironic require- JUNE 2005 WORLD AIDS SNAPSHOT MOST OF THE GLOBE’S 40 million people infected with HIV live in sub-Saharan Africa and South and Southeast Asia, as reflected in the ranking below, which is based on 2001 data from the Joint United Nations Program on HIV/AIDS. There are five major strains of HIV, which are also called clades. Although more than one clade can usually be found in any given area, the map highlights the predominant clade affecting each region.
Department of Defense were scheduled to conduct essentially duplicate 36 trials of the vaccine. But NIAID pulled the plug on its trial after an examination of the data from a phase II study showed that fewer than 30 percent of the volunteers generated cytotoxic T cells against HIV. And in a bureaucratic twist, this past January the White House transferred the budget for the Defense Department trial over to NIAID as part of an effort to streamline AIDS research. ” Critics cite these machinations as a case study of politics getting in the way of progress against AIDS.
Langridge FOODS UNDER STUDY as alternatives to injectable vaccines include bananas, potatoes and tomatoes, as well as lettuce, rice, wheat, soybeans and corn. 38 SCIENTIFIC AMERICAN EXCLUSIVE ONLINE ISSUE JUNE 2005 COPYRIGHT 2005 SCIENTIFIC AMERICAN, INC. JOHNSON & FANCHER V accines have accomplished near miracles in the fight against infectious disease. They have consigned smallpox to history and should soon do the same for polio. By the late 1990s an international campaign to immunize all the world’s children against six devastating diseases was reportedly reaching 80 percent of infants (up from about 5 percent in the mid1970s) and was reducing the annual death toll from those infections by roughly three million.
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