By Caroline Gordon, David Isenberg
Systemic Lupus Erythematosus offers a realistic method of the evaluate and administration of sufferers with this advanced, multisystem autoimmune illness to enhance the analysis and remedy of the sickness and its complications.
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Extra resources for Systemic lupus erythematosus
Sample text
Many studies, including the SLICC international mortality study with data up to 200, have shown that the highest SMRs are seen in young patients with lupus, for whom the risk of dying would otherwise be very low. 0). 5). More recent studies from Birmingham, UK have shown that there is still at least a five times higher risk of dying from lupus aged 20–24 than for that age in England and Wales overall, despite care in a dedicated lupus centre where patients have access to a national health service at all times.
The median age at death was 64 years. 5% at 0 years, and 73% at 5 years. Cardiovascular events accounted for 32% of deaths, 6% were due to respiratory system disease, with 3% dying from malig40 nancies. There were few deaths due to active lupus or infection except in the newly diagnosed. 034). 008). 05). 78). All-cause mortality decreased from 975 to 995 due to a reduction in deaths attributed to SLE, but cardiovascular disease remained a major cause of death even in young patients in the last decade studied.
Emerging role of IL-7 and Th7 cells in systemic lupus erythematosus. Clin Immunol 204;54:–2. Deng Y, Tsao BP. Advances in lupus genetics and epigenetics. Curr Opin Rheumatol 204;26:482–92. 7. Finckh A, Cooper GS, Chibnik LB, et al. Occupational silica and solvent exposures and risk of systemic lupus erythematosus in urban women. Arthritis Rheum 2006;54:3648–54. Costenbader KH, Gay S, Alarcon-Riquelme ME, Iaccarino L, Doria A. Genes, epigenetic regulation and environmental factors: which is the most relevant in developing autoimmune diseases?