By Yao He, Yuanyuan Su (auth.)
This booklet studies the most recent advances within the improvement of silicon nano-biotechnology for organic and biomedical functions, which come with biosensing, bioimaging, and melanoma treatment. during this ebook, newly built silicon nano-biotechnology and its biomedical purposes are systematically brought. for example, fluorescent silicon nanoparticles, serving as novel high-performance organic nanoprobes, are fantastically fitted to real-time and long term bioimaging. Silicon nanowire-based sensing platform is principally in a position to delicate, particular, and multiplexed detection of assorted organic species. Silicon-based nanocarriers with ultra-high drug-loading skill are hugely efficacious for in vitro and in vivo melanoma remedies.
This booklet is meant for readers who're attracted to the layout of sensible silicon nanostructures and their organic and biomedical purposes. It makes use of silicon nanoparticles and silicon nanowires as types and discusses themes starting from their synthesis to their organic purposes, the objective being to focus on those fascinating achievements as beginning issues within the box of silicon nano-biotechnology.
Yao He is a Professor at Institute of useful Nano&Soft fabrics (FUNSOM), Soochow collage, China.
Yuanyuan Su is an affiliate Professor at Institute of practical Nano&Soft fabrics (FUNSOM), Soochow collage, China.
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Scan rate 50 mV/s. c Amperometric i–t curves of the Nafion-GOxAuNPs@SiNWs/GC electrode for various glucose concentrations. d Calibration curve of the Nafion-GOx-AuNPs@SiNWs/GC electrode. Reproduced from Ref. [76] with permission from the Royal Society of Chemistry on an electrode made of SiNWs coated with gold nanoparticles (AuNPs) (AuNPs@SiNWs) (Fig. 8a) [76]. Such AChE-based sensors were highly efficacious for rapidly detecting organophosphorous (OP) with enhanced enzymatic activity of AChE. As a result, the resultant sensing device exhibited high sensitivity, enabling detection of low-concentration (8 ng/L) dichlorvos (DDV), an OP pesticide [75].
Gold and silver NPs have been widely employed as SERS substrates for biomolecules detection in the past decade [89, 90].