By H. J. G. Gundersen (auth.), Luigi F. Agnati, Kjell Fuxe (eds.)

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Read or Download Quantitative Neuroanatomy in Transmitter Research: Proceedings of an International Symposium held at The Wenner-Gren Center, Stockholm,May 3–4, 1984 PDF

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Extra resources for Quantitative Neuroanatomy in Transmitter Research: Proceedings of an International Symposium held at The Wenner-Gren Center, Stockholm,May 3–4, 1984

Sample text

FILM consists of many of the functions of TRACE, MICRO and RAn with special routines to control the film advance and film transport micropositioning syst8Ill. In this way the serial electron microscope reconstruction methods pioneered by Levinthal and associates (Macagno, et. , 1979) can be included with minimal special purpose programming. Finally, a future planned acquisition mode will be GEL, a system for study of the spots visualized by two dimensional gel electrophoresis method for separation of proteins.

All data is physically stored in a binary file Which is treated as an extension of the program's address space. The virtual merrory software package can address any element of the file through 32-bit pointers to byte locations. Tasks in computer-assisted neuroanatomy 33 Figure 3. (Upper) Three dimensional distribution of thalamic cells projecting to 51 peri-oral regions in rat. View looking into thalamus fran behind. ) HRP labelled cells (blue) ShONO at lower left in VentroPosteroMedial (VPM) nucleus.

The fact that size distributions of neuronal somata, dendrite internode lengths and synaptic areas all appear to be highly positively skewed has been reported by Howard and Scales (198Z) and Howard (1983). The theoretical evaluation and functional significance of highly asymmetric size distributions in biological systems has been dealt with by Howard (1981a, 1981b and 1983). When highly restricted patterns of biological variation are found, then they usually indicate strong selection pressures acting upon the system under consideration.

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