By James E. Tcheng

The previous 50 years have witnessed a wide ranging evolution within the methods to the sufferer with an acute ST elevation myocardial infarction. within the Sixties, the now common cardiac extensive care unit used to be yet a nascent suggestion. with no a lot to provide the sufferer yet weeks of absolute bedrest, colossal morbidity and excessive charges of mortality have been the norm. simply 30 years in the past, seminal discoveries by way of DeWood and co-workers prompt that the perpetrator was once plaque rupture with thrombosis, now not revolutionary luminal compromise. next fibrinolyt- established recommendations ended in a halving of the mortality of acute myocardial infarction. With the advent of balloon angioplasty within the past due Seventies, a couple of interventional cardiologists braved the query: why now not practice emergency angioplasty as a chief reperfusion procedure? certainly, stories of profitable reperfusion through balloon angioplasty seemed (mostly in neighborhood newspapers) as early as 1980. regardless of being regarded as heretical by way of mainstream cardiology, those pioneers still endured, proving the advantage of ‘‘state-of-the-art’’ balloon angioplasty in comparison with ‘‘state-of-t- art’’ thrombolytic treatment in a sequence of landmark trials released within the New England magazine of drugs in March of 1993. book of the 1st version of basic Angioplasty in Acute Myocardial Infarction in 2002 to a point expected the frequent reputation of fundamental percutaneous coronary intervention because the common of care. in view that then, in all respects, the evolution of emergency percutaneous revascularization has simply speeded up. The common alternative of balloon angioplasty with stent implantation was once basically one key.

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Extra resources for Primary Angioplasty in Acute Myocardial Infarction (Contemporary Cardiology)

Sample text

Final TIMI flow after PCI, however, remains a critical predictor of mortality both at 30 d and at 1 yr. Regardless of the initial TIMI flow, interventional cardiologists must strive to achieve TIMI 3 flow on the final angiogram when performing acute PCI. Final TIMI 3 flow results in improved mortality both in stent and balloon angioplasty patients when compared to TIMI 2 or 0–1 flow on the final angiogram (27). Successful PCI of an occluded infarct artery first requires successful wiring of the lesion.

Final TIMI flow after PCI, however, remains a critical predictor of mortality both at 30 d and at 1 yr. Regardless of the initial TIMI flow, interventional cardiologists must strive to achieve TIMI 3 flow on the final angiogram when performing acute PCI. Final TIMI 3 flow results in improved mortality both in stent and balloon angioplasty patients when compared to TIMI 2 or 0–1 flow on the final angiogram (27). Successful PCI of an occluded infarct artery first requires successful wiring of the lesion.

6. Ross AM, Lundergan CF, Rohrbeck SC, et al. Rescue angioplasty after failed thrombolysis: technical and clinical outcomes in a large thrombolysis trial. J Am Coll Cardiol 1998;31:1511– 1517. 7. Grines CL, Cox DA, Stone GW, et al. Coronary angioplasty with or without stent implantation for acute myocardial infarction. N Engl J Med 1999;341:949–956. 8. Stone GW, Grines CL, Cox DA, et al. A prospective, randomized trial comparing balloon angioplasty with or without abciximab to primary stenting with or without abciximab in acute myocardial infarction—primary endpoint analysis from the CADILLAC trial.

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