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MANI and NARASIMHAN (1973) have described the kits prepared at Bhabha Atomic Research Centre, in Trombay, India. The kits have the advantage of a well-standardized method of preparation of radiopharmaceuticals and the producers look for optimizing the conditions of preparation-the simplest and the fastest. The following are known kits for eluating generators, and kits for technetium radiopharmaceuticals: sulphur colloids, DTPA, human serum albumin, phosphate, macroaggregates, Generators and Kits 21 microspheres, kits for indium radiopharmaceuticals: gelatine, transferrin, iron hydroxide colloid, DTPA, etc.
1. 5 diiodofluorescein is prepared either by direct iodination of fluorescein or by an exchange reaction with the iodinated nonradioactive coumpound. Diiodofluorescein is a red-orange substance, insoluble in water in acid form, soluble in alkaline solutions. Diiodofluorescein is used for localization of brain and eye tumors. 28 2. Rose bengal e Y. COHEN and M. BESNARD: Radionuclides. Pharmacokinetics 31 I) Cl NaO Rose bengal, or 2, 4, 5, 7 tetraiodo 3', 4', 5', 6' tetrachlorofluorescein, is used as the disodium salt, soluble in water, forming a deep red solution.
Usually the radionuclidic purity is higher than 99 %. , 1974). Antimony of antimony trisulphide is enriched in 121Sb to 95 %. 123 1 will occupy in the future an important field and replace progressively 131 I not only. as the sodium iodide radiopharmaceutical, but also for labeling such organic molecules as hippurate, iodoantipyrine, macro aggregates, etc. The new iodinating method developped by EL-GARHY and STOCKLIN (1974) seems particularly attractive. 4. 18F. Only one radioisotope of fluorine is usable thanks to its relatively long half-life (11 0 min): it is 18F.