By Brian P. Griffin, Eric J. Topol

Completely revised and up to date, this pocket-sized handbook is an variation of Topol's Textbook of Cardiovascular medication, 3rd variation. The 3rd version of this best-selling guide follows a similar constitution as past versions, utilizing an summary structure with key phrases and words highlighted in daring. The concise textual content presents quick access to the knowledge had to deal with sufferers with heart problems and is acceptable for citizens, fellows, working towards cardiologists, and nurse-practitioners. This most up-to-date revision offers up to date medical info and has 8 new chapters, together with weight problems and metabolic syndrome, ladies and center affliction, and center failure therapy.

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Extra resources for Manual of Cardiovascular Medicine, 3rd Edition

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LA, C;nnes CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitatIve revIew of 23 randOlTIIsed trid\<;. Lancet 2003;361: 13-20. Ander<;en HR, Nicl ... en "fT, Ra'>mussen K. et al. udul infarction. N b1glI IvIed 2003; :;49:733-742. , Grine~ LL, et al. A randomized trial of tramfer for pnmary angioplasty versus ()n-~ite thrombolysis in patIents WIth high-risk myocardiJI mfarctlOn: the Air Pnmary Angi()p1a~ty ill MY

Chen YP, et al. Addition of clopidogrc! to a'>pirin in 45,852 patients with acute myocardial tnfan. lI1dOmlScd pbcebo-controlled tna!. J. onct't 1005;366: 1 h07-1 n21. VI, Armstrong P\Xl, ct ,11. ~sociatlon Ta~k force on Practice C;uidelines. J Am CoIl Cardwl 2008;51 :21 0-247. ;;uf S, Collin'> R, MacMahon \ et al. ;;. jjlncet 19RR; 1: 1OHH-l 092. \1ehdli J, Anroniucci D, et al. ' IAMA 2005;293:28652H72. lA, C;nnes CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitatIve revIew of 23 randOlTIIsed trid\<;.

The EXTRACT-TIM! 25 trial did not have a primary PCI subset, however, among patients who underwent subsequent PCI after fibrinolysis, cnoxaparin appeared to be superior to UFH without increased bleeding events (31). Fondaparinux is an additional low-molecular weight heparin that has been studied in acute MI. 7';;, vs. Sh) without an increased risk in bleeding (49). However, in the primary PCI subset, there was no benefit and a significant increase in guiding-catheter thrombosis, which has limited its widespread use.

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