By Katharina Nimptsch, Edward Giovannucci (auth.), Derek LeRoith (eds.)
The e-book will element the heritage, successes, and screw ups of precise treatments for melanoma, with a selected concentrate on IGF platforms and cancer.
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When neoplastically transformed liver epithelial cells were transplanted into rats of different ages their tumorigenic potential increased with advancing age of the recipient rats (McCullough et al. 1994). In contrast, when rhabdomyosarcoma cells were inoculated into rats of different ages the number of resulting lung tumours was greatest in the youngest rats and correlated positively with the IGF-I-activity in the lung (Anisimov et al. 1988). There is also some clinical evidence that age-related changes in the internal milieu affect tumour growth.
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