By Ph.D. Horn;Alan Hecht Lyle W.

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Additional resources for Hepatitis (Deadly Diseases and Epidemics)

Example text

Lost work in an underdeveloped country can be very serious, however. Poor people have limited opportunities for work. Subsistence farmers could lose a harvest and an entire family could face starvation. The high incidence of hepatitis A in underdeveloped countries is important for public health in the United States, Europe, and Japan. Many foodstuffs, especially fresh fruits and vegetables, are imported from underdeveloped countries in our global economy. The produce is likely to be handled by a hepatitis A virus carrier and washed with contaminated water before being shipped.

Radioimmunoassay and Immunofluorescence A blood sample is treated with an antibody that is labeled with a radioactive material in a radioimmunoassay (RIA), or with a molecule that glows when a light shines on it, in an immunofluorescence assay. If an antigen is present, the antibody binds to it and the complex can be detected by sensitive measuring techniques. ELISA A second method of establishing that a virus infection is present is the detection of specific antibodies in the blood (see Chapter 4).

These molecules have a chemical property that classifies them as bases. They also like to link up loosely with each other to form base pairs in a very specific manner. They never link up with the other bases. Thus, we get the pairs A–T and C– G, and no others. When an adenine on one DNA strand is opposite a thymine on the other strand, the two link up. The same thing happens between cytosine and guanine. In fact, the two strands are synthesized to be complementary so that opposite bases always link up.

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