By Clive Niels Svendsen, Allison D. Ebert

What is a stem cellphone? we've got a easy operating definition, however the manner we become aware of a stem phone functionality in a dish would possibly not signify the way it features in a residing organism. purely this is often transparent: Stem cells are the engine room of multicelluar organisms-both crops and animals. although, controversies, breakthroughs, and frustration proceed to swirl in everlasting storms via this speedily relocating quarter of study. yet what does the common individual make of all this, and the way can an pupil probe this mammoth sea of information.

The Encyclopedia of Stem telephone Research presents a transparent realizing of the elemental recommendations in stem mobile biology and addresses the politics, ethics, and demanding situations at present dealing with the sphere. whereas stem cells are intriguing on my own, also they are truly fueling the normal components of developmental biology and the sphere of regenerative medication. those volumes current greater than 320 articles that discover significant subject matters regarding the rising technological know-how of stem mobilephone examine and treatment.

Key Features

· Describes the differing kinds of stem cells which have been stated thus far and, the place attainable, attempts to give an explanation for for every age, tissue, and species what's identified in regards to the biology of the cells and their history

· Captures a robust feel of stem telephone biology because it stands this present day and gives the reader with a reference guide to probe the mysteries of the field

· Considers numerous non secular, criminal, and political perspectives

· comprises chosen reprints of significant magazine articles that pertain to the milestones completed in stem cellphone research

· Elucidates stem cellphone terminology for the nonscientist.

Key Themes

· Biology
· medical Trials
· Countries
· Diseases
· Ethics
· historical past and Technology
· Industry
· associations
· Legal
· Organizations
· People
· Politics
· Religion
· States

With contributions from students and institutional specialists within the stem telephone and social sciences, this Encyclopedia offers a essentially nonscientific source to realizing the complexities of stem mobile learn for tutorial and public libraries.

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In addition, no cell-related adverse events were observed, and none of these patients have required hip replacement surgery. These data demonstrate, for the first time, that Aastrom’s cell products may have a beneficial longterm effect in two key indications: critical limb ischemia and osteonecrosis of the femoral head. Although still in their early stages, these results lend substantial scientific support to the clinical development program focused on autologous stem cell products for regenerative medicine.

In addition, every exogenous cell type used (BMCs, skeletal myoblasts, embryonic myo- cytes, and endothelial cells), although capable of enhancing cardiac function, behaved as a passive graft acquiring a rather immature aspect and enhanced overall cardiac function modifying the biomechanical properties of the scarred portion of the heart. Embryonic stem cells, which have also been proposed as exogenous progenitor cells, have tumorigenic properties and would represent a heterologous source: Because they express HLA class I antigens in discrete quantities, they could induce an immune response.

It is in the ventral (anterior) horn that the UMN synapses, or connects, with the lower motor neuron LMN, which carries information from the spinal cord outward to its target. ALS is a disease that primarily affects the motor half of the nervous system. Pathology of ALS In ALS, both the UMNs and the LMNs degenerate. The disease is characterized by the loss of motor neurons that are subsequently replaced by glia, or other supporting cells of the nervous system. On magnetic resonance imaging (MRI) of the brain, bilateral white matter changes can be appreciated.

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