By Jyothi Rengarajan, Laurie H. Glimcher (auth.), Vijay K. Kuchroo DVM, PhD, Nora Sarvetnick PhD, David A. Hafler MD, Lindsay B. Nicholson PhD, MB (eds.)
Although the function of cytokines and chemokines within the induction and legislation of autoimmunity has an unlimited present literature, there's as but no transparent consensus concerning the info of this complicated method. In Cytokines and Autoimmune ailments, major researchers synthesize the to be had info to aid strengthen an intimate realizing of ways cytokines and chemokines are fascinated with the pathogenesis of autoimmune ailments. the various chapters supply severe reports of the elemental mechanisms controlling cytokine induction and law, in addition to the ensuing creation of proinflammatory and anti inflammatory cytokines, the previous of which induces organ-specific autoimmune illnesses. From the vantage of those insights, they deal with the function of cytokines in a large choice of autoimmune ailment, uvetis, encephalomyelitis, a number of sclerosis, human variety 1 diabetes, rheumatoid arthritis, SLE, and myasthenia gravis.
Authoritative and cutting-edge, Cytokines and Autoimmune illnesses comprehensively integrates the diffuse literature of this dramatically advancing box, and highlights the large healing power of cytokine modulation within the therapy of autoimmune disease.
Read Online or Download Cytokines and Autoimmune Diseases PDF
Similar diseases books
This can be a 3-in-1 reference ebook. It provides an entire scientific dictionary protecting thousands of phrases and expressions when it comes to gynecomastia. It additionally offers wide lists of bibliographic citations. eventually, it offers details to clients on tips on how to replace their wisdom utilizing a number of web assets.
Imaging of Perianal Inflammatory Diseases
This sensible quantity is meant for all radiologists, gastroenterologists, and surgeons who're answerable for, or drawn to, the prognosis and care of sufferers with ailments of the anal and perianal sector. After an introductory part targeting surgical, MRI, and US anatomy, up to date scientific and healing details is supplied at the complete diversity of perianal inflammatory stipulations, with distinct consciousness to Crohn’s disorder, ulcerative colitis, and sexually transmitted illnesses.
Diseases of the Brain, Head and Neck, Spine: Diagnostic Imaging and Interventional Techniques
The foreign Diagnostic direction in Davos (IDKD) deals a different studying event for imaging experts in education in addition to for knowledgeable radi ologists and clinicians wishing to be up to date at the present cutting-edge and the newest advancements within the fields of imaging and image-guided interventions.
Cell Adhesion Molecules: Implications in Neurological Diseases
Mobilephone Adhesion Molecules: Implications in Neurological ailments comprises evaluate articles on fresh advancements within the box of neural mobile adhesion molecules (CAMs). the main target is at the position of mobile adhesion molecules in a number of neurological and neurodegenerative illnesses. this attitude has been primarily ignored in lately released books on neural CAMs.
- Primer on the Rheumatic Diseases
- Allergic diseases - highlights in the clinic, mechanisms and treatment
- A New Model for Health and Disease
- Pain Medicine and Management
- Angel of Death: The Story of Smallpox
Additional resources for Cytokines and Autoimmune Diseases
Example text
J. BioI. Chem. 274, 6698 . , Jacobson, N. , Gorham, J. , Sha, W. , et al. (1999) The Ets transcription factor ERM is Th l-specific and induced by IL-12 through a Stat4-dependent pathway. Proc . Nat!. Acad. Sci. USA 96, 3888-3893. Rengarajan, J. , Mittelstadt, P. , Mages, H. , Gerth, A. , Kroczek , R. , Ashwell , J. , and Glimcher , L. H. (2000) Sequential involvement ofNFAT and Egr transcription factors in FasL regulation . Immunity 12, 293-300. Szabo, S. , Kim, S. , Costa , G. , Fathman, C. , and Glimcher, L.
Sci. USA 93,9358-9365 . 19. Thomas, R. , Tymms, M. , McKinlay, L. , Shannon, M. , Seth, A. , and Kola, I. ( 1997) ETSI , NF-kappaB and API synergistically tran sactivate the human GM-CSF promoter. Oncogene 14, 2845-2855 . 20. Rao, A . (1994) NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes. Immunoi. Today 15, 274-281 . 21. , and Hogan P. G. (1997) Transcription fact ors of the NFAT famil y: regu lation and function . Annu. Rev. Immunoi. 15, 707- 747.
Butscher, W. , Powers, C. , and Gardner, K. (1998 ) Coordinate transactivation of the interleukin-2 CD28 response element by cRei and ATF-I/CREB2. J. BioI. Chem. 273,552-560. 37. , and Dohlsten, M. (1998 ) Overexpression of p65 and c-Jun sub stitutes for B7-1 costimulation by targeting the CD28RE within the IL-2 promoter. J. Immunol. 160,5374-5381. 38 . McGuire, K. and Iacobelli, M. (1997) Involvement of ReI, Fos, and Jun proteins in binding activity to the IL-2 promoter CD28 response element/AP-I sequence in human T cells.
- Download Traum und Traumdeutung als by Paul Diepgen PDF
- Download 21 cm — Untersuchungen zur Struktur und Dynamik der by Bernd-Harald Grahl PDF