By Oscar B. Garfein
Read or Download Current Concepts in Cardiovascular Physiology PDF
Best cardiovascular books
Angiogenesis Assays: A Critical Appraisal of Current Techniques
Content material: bankruptcy 1 Endothelial cellphone Biology (pages 1–38): Femke Hillen, Veerle Melotte, Judy R. van Beijnum and Arjan W. GriffioenChapter 2 Endothelial mobilephone Proliferation Assays (pages 39–50): Wen? Sen LeeChapter three Endothelial phone Migration Assays (pages 51–64): Christos Polytarchou, Maria Hatziapostolou and Evangelia PapadimitriouChapter four Tubule Formation Assays (pages 65–87): Ewen J.
Diabetes and Cardiovascular Disease
During this moment variation of Diabetes and heart problems, Michael T. Johnstone, MD, and Aristidis Veves, MD, have up to date and extended their very profitable vintage textual content to mirror new examine, advances in scientific care, and the growing to be reputation that diabetes mellitus is a possibility issue for heart problems.
Pediatric Electrocardiography: An Algorithmic Approach to Interpretation
This ebook elucidates the method of analyzing electrocardiograms (ECGs) in teenagers. It offers a established, step by step advisor for studying ECGS utilizing algorithms, which enable clinicians to decipher the information inside of those tracings and determine differential diagnoses. The booklet additionally offers real high-definition ECG tracings, that are annotated and highlighted to illustrate the problems mentioned.
- Basis and Treatment of Cardiac Arrhythmias
- Metabolic Syndrome and Cardiovascular Disease, Second Edition
- The ECG in Practice
- Making Sense of Echocardiography: A Hands-on Guide
- Chest radiographic interpretation in pediatric cardiac patients
Extra info for Current Concepts in Cardiovascular Physiology
Example text
The regulation of flux through 2-oxoglutarate dehydrogenase is complex and is still not well understood. , 1981), and (2) the availability of free coenzyme A , a cofactor for the reaction (Taegtmeyer, 1983). IX. PHYSIOLOGICAL IMPLICATIONS The effects of increased cardiac work on cardiac metabolism are mediated by a feedback system which keeps energy production in step with energy utilization on a beat-to-beat basis. The effects of cardiac work have already been considered in conjunction with individual fuels for respiration.
As shown in Fig. 10, in heart muscle pyruvate may either be reduced to lactate (which completes the glycolytic pathway), transaminated to alanine, carboxylated to oxaloacetate or malate, or, most impor tantly, oxidized to acetyl-CoA. Lactate and most of the alanine are formed in the cytosol by near-equilibrium reactions and both metabolites may be washed out from the cell. In well-oxygenated working heart muscle the bulk of pyruvate C H - - CM - COOH CMj-CM-COOM co 2 1/ HOOC-CHj-^-COOH Ο Q « a l o a c e t a te MOOC-CHj -(^H-COOH OH Malate H C-C~SCoA 3 Acetyl-CoA Figure 10.
Data such as these are, however, few, and it is hoped that more will be learned on the integrative control of cardiac metabolism in the future. It needs to be stressed that control of flux through a metabolic pathway cannot be achieved by any single enzyme act ing in isolation and that regulation is a shared property of many different intraand extracellular effectors. X. PATHOPHYSIOLOGICAL IMPLICATIONS: METABOLIC ALTERATIONS IN MYOCARDIAL ISCHEMIA A. Coupling of Coronary Flow to Mechanical and Metabolic Activities It cannot be emphasized too strongly that the heart has a high rate of energy turn over.