By Oriol Bachs Ph.D., Neus Agell Ph.D. (auth.)

This e-book is ready the position of calcium and calmodulin within the cellphone nucleus. Calcium, that's an enormous moment messenger of sign transduction pathways, may also function within the phone nucleus. diversified calcium binding proteins, that are the pursuits of mobile calcium, were pointed out within the nucleus of many alternative cellphone kinds. popular between those calcium binding proteins is calmodulin, which seems to be keen on the law of significant nuclear capabilities akin to gene expression and DNA replication.

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Extra resources for Calcium and Calmodulin Function in the Cell Nucleus

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CeH Calcium 1994; 15:55-65. 16. Himpens B, De Smedt H, Casteels R. Intracellular signalling induced by vasopressin, ATP and EGF in renal epithelial LLC-PK 1 cells. Am J Physiol 1993; 265:C966-C975. Nuclear Calcium and its Regulation 33 17. Williams DA, Becker Pl, Fay FS. Regional changes in calcium underlying cootraction of single smooth muscle ceHs. Science 1987; 1644-1648. 18. Himpens B, De Smedt H, Casteels R. Kinetics of nucleocytoplamsatic transieots in DTT 1MF-2 smooth muscle ceHs. Am J Physiol 1992; 263:C978-C985.

Biochimica et Biophysica Acta 1992; 1123:259-270. 6. Himpens B, De Smedt H, Casteels R. Relation between [Ca2+] changes in nucleus and cytosol. Cell Calcium 1994;16:239-246. 7. Hernandez-Cruz A, Sala F, Adams PR. Subcellular calcium transients visualized by confocal microscopy in a voltage-clamped vertebrate neuron. Science 1990; 247:858-862. 8. Tsunoda Y, Matsuno K, Tashiro Y. Spatial distribution and temporal change of cytoplasmic free calcium in human platelets. Biochem Biophys Res Commun 1988; 156:1152-1159.

Science 1987; 1644-1648. 18. Himpens B, De Smedt H, Casteels R. Kinetics of nucleocytoplamsatic transieots in DTT 1MF-2 smooth muscle ceHs. Am J Physiol 1992; 263:C978-C985. 19. Himpens B, De Smedt H, Droogmans G, Casteels R. Differences in regulation between nuclear and cytoplasmatic Ca2 + in DDT1MF2 smooth muscle ceHs. Am J Physiol 1992; 263:C95-CI05. 20. Lipscombe D, Madison DV, Poenie M et al. Spatial distribution of calcium channels and cytosolic calcium transients in growth cones and ceH bodies of sympathetic neurons.

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