By Francis Ali-Osman

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Et al. 2001. Assembly of microarrays for genome-wide measurement of DNA copy number. Nat. Genet. 29:263–264. 85. , et al. 1997. 3 that is mutated in multiple advanced cancers. Nat. Genet. 15:356–362. 86. , et al. 1998. Selective sensitivity to radiation of cerebral glioblastomas harboring p53 mutations. Cancer Res. 58:1793–1797. 87. M. 1998. Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science 280:1614–1617. 88. , et al. 1997. Molecular genetic analysis of the von Hippel-Lindau disease tumor suppressor gene in familial and sporadic cerebellar hemangioblastomas.

Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system. Cancer Res. 58:1798–1803. 70. , et al. 1996. Refined deletion mapping of the chromosome 19q glioma tumor suppressor gene to the D19S412-STD interval. Oncogene 13:2483–2485. 71. , et al. 1994. Mutations of the neurofibromatosis type 2 gene and lack of the gene product in vestibular schwannomas. Hum. Mol. Genet. 3:885–891. 72. , et al. 1999. Cyclin-dependent kinases: initial approaches to exploit a novel therapeutic target.

Et al. 1997. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275:1943–1947. 43. , et al. 1985. Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin. Nature 313:144–147. 44. , et al. 1998. Allelic deletion analyses of MMAC/PTEN and DMBT1 loci in gliomas: relationship to prognostic significance. Clin. Cancer Res. 4:2447–2454. 45. , et al. 1995. Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16.

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