By Ron Waksman, John A. Ormiston

This is specialist suggestions on some of the most vexing scientific demanding situations confronted via interventional cardiologists. Written via worldwide idea leaders within the sector and edited by means of internationally-recognized pioneers in interventional cardiology, Bifurcation Stenting covers all recommendations, imaging modalities, and units in present use, together with VH-IVUS and OCT. It contains functional tips/tricks from prime specialists and a piece of difficult circumstances to additional illustrate the fabric and aid readers larger comprehend the therapy of bifurcation lesions.

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Physiologic assessment of jailed side branch lesions using fractional flow reserve. J Am Coll Cardiol 2005;46 (4):633–7. Pomerantz RM, Ling FS. Distortion of Palmaz-Schatz stent geometry following side- branch balloon dilation through the stent in a rabbit model. Cathet Cardiovasc Diagn 1997;40:422–6. Ormiston JA, Webster MW, Ruygrok PN, Stewart JT, White HD, Scott DS. Stent deformation following simulated side-branch dilatation: a comparison of five stent designs. Catheter Cardiovasc Interv 1999 Jun;47(2): 258–64.

The fourth Nordic bifurcation study is aimed at comparing a simple one-stent strategy with a twostent strategy (with preference for the culotte technique) for true bifurcation lesions with server lesions in large SBs. The study setup is like the previous Nordic Bifurcation studies featuring 6-month clinical and 8-month angiographic follow-up. An optical coherence tomography single center substudy was added to provide further insight in acute and follow-up results at stent strut level. Patients are eligible for inclusion if the true bifurcation lesion is located in vessels measuring MV !

The difference made the results of the LMCA substudy difficult to interpret, although the rate of MACCE was similar for PCI and CABG in this subset of patients. 009)) compared to PCI. The limitations of SYNTAX LMCA were the substudy design and the use of a paclitaxcel eluting stent, which is associated with increased risk of late stent thrombosis, myocardial infarction and death [32–34] The NOBLE study was designed to overcome these limitations by a dedicated LM study design and use of a second generation DES.

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