By Isadore Meschan

Publication by means of Meschan, Isadore

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Cartilage grows by one of two methods: 1 . Interstitial growth , in which the cartilage cells themselves retain their capacity to divide. This capacity is retained by young cartilage cells only. These ce1\s are responsible for the addition of intercellular substance, which enables the cartilage to expand from within. 2. Appositional growth is defined as the adding of new carti­ lage to a preexisting surface, and is caused by differentiation of the deep perichondrial cells into chondroblasts and later to chon­ drocytes.

In doses exceeding 3000 or 4000 rads, additional deleterious effects upon the central nervous system occur. Fortunately, dramatic protection is afforded the body by shielding even a part of it from ionizing radiation. For example, if only one leg is thoroughly shielded, the chance of survival is markedly increased; and of course, irradiation of only a small part of the body has far less dramatic effects. In therapeutic radiology, it is not uncommon to administer 5000 to 6000 rads over a period of 5 to 6 weeks to a given small area of the body in treatment of a malignant tumor, with only moderate or negligible systemic effects.

Physical Foundations Qf Radiology. New York, Paul B. Hoeber, 1952. Grigg, E. R. : The Trail of the Invisible Light. , Charles C Thomas, 1965. Hildreth, E. A . Pendergrass, H. , Tondreau, R. : Reactions associated with in- FUNDAMENTAL BACKGROUND FOR RADIOLOGIC ANATOMY travenous urography; discussion of mechanisms of therapy. Radiology, 74:246-254, 1960 (36 references). Marshall, T. , and Ling, J. : Clinical evaluation of two new contrast media: Con ray and Angio­ conray. Amer. J. , 89:423-431 , 1963.

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