By Ute Resch-Genger, Markus Grabolle, Roland Nitschke, Thomas Nann (auth.), Alexander P. Demchenko (eds.)
From the reviews:
“This publication is a complete assessment of the different sorts of nanoscale probes which have been and are presently being built for sensing of analytes. The well timed reference part permits the reader to find key references to the first literature for growth of the cloth lined. … a beneficial source that covers the substitute, photo-physical, and theoretical elements of this assorted box of research.” (Jeffrey T. Petty, magazine of the yankee Chemical Society, Vol. 133, 2011)
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Extra resources for Advanced Fluorescence Reporters in Chemistry and Biology II: Molecular Constructions, Polymers and Nanoparticles
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Angew Chem Int Ed 44:4550–4554 17. Prodi L, Battistini G, Dolci L, Montalti M, Zaccheroni N (2007) Luminescence of gold nanoparticles. In frontiers in surface nanophotonics, Springer series in optical sciences. 1007/ 978-0-387-48951-3_5 18. Fu H, Yao JN (2001) Size effects on the optical properties of organic nanoparticles. J Am Chem Soc 123:1434–1439 19. Soukka T, Rantanen T, Kuningas K (2008) Photon upconversion in homogeneous fluorescence-based bioanalytical assays. Ann N Y Acad Sci 1130:188–200, Fluorescence Methods and Applications: Spectroscopy, Imaging, and Probes 20.
This is similarly true for metal ligand complexes and lanthanide chelates, the application of which in FRET pairs is not further detailed here. , TR-FRET assays) [10, 54]. 5 Multiplexing Detection Schemes Current security and health concerns require robust, cost-effective, and efficient tools and strategies for the simultaneous analysis, detection, and often even quantification of multiple analytes or events in parallel. The ability to screen for and quantify multiple targets in a single assay or measurement is termed multiplexing.
For unmodified cadmium telluride QDs, the induction of the formation of ROS formation leading to multiple organelle damage and cell death has been reported [92]. The preparation of both, the particles themselves and the protective surface layer, has direct influence on their cytotoxicity. It is common belief that in the case of core/shell nanoparticles, properly prepared, close shell or multiple shells such as ZnS/SiO2-shells prevents the leakage of toxic elements and thus makes cytotoxicity unlikely.